Bilateral Calvarial Infarctions That Lead to Epidural Hematomas in a Patient With Sickle Cell Disease

Calvarial infarctions are a rare but serious complication of sickle cell disease. The initial clinical presentation may be limited to a nonspecific finding, such as headache, and the radiographic changes may, initially, be minimal. However, subsequently calvarial infarctions may lead to additional complications such as epidural hemorrhage. This case provided an excellent example of a rare but important presentation and allows the reader to see examples of radiographic findings at multiple stages of clinical development.