Perinatal Stroke as It is: Updates, Insights and Challenges
Perinatal stroke comprises a heterogeneous group of focal cerebrovascular injuries that occur between 20 weeks of gestation and 28 days of postnatal life. Perinatal stroke is a leading cause of life-long disability, causing most cases of hemiparetic cerebral palsy. The
intent of this article was to provide a comprehensive review of the 6 different types of perinatal stroke based on neuroimaging and clinical presentation, highlighting their similarities and distinctions in etiology and outcome, and further discuss a neuroimaging pathway for suspected perinatal
stroke and follow-up imaging.
Learning Objective: To provide an update on the current knowledge of the role of neuroimaging in diagnosis and long-term prognosis of perinatal stroke diseases and to understand the microglial role in perinatal arterial stroke
Learning Objective: To provide an update on the current knowledge of the role of neuroimaging in diagnosis and long-term prognosis of perinatal stroke diseases and to understand the microglial role in perinatal arterial stroke
Keywords: ACA = anterior cerebral artery; APPIS = arterial presumed perinatal ischemic stroke; CHD = congenital heart disease; CSVT = cerebral sinovenous thrombosis; GRE = gadient-recalled echo; HIE = hypoxic-ischemic encephalopathy; NAIS = neonatal arterial ischemic stroke; NHS = neonatal hemorrhagic stroke; PC = phase-contrast; PCA = posterior cerebral artery; PPHS = presumed perinatal hemorrhagic stroke; PVI = periventricular venous infarct; cUS = cranial ultrasound; pCASL = pseudocontinuous arterial spin-labeling
Document Type: Research Article
Publication date: 01 February 2024
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