Perivascular Spaces: Neuroimaging, Microanatomy, Homeostasis, and Pathophysiologic Mechanisms of Disease
Learning Objective: To describe the normal anatomy and variable appearance of perivascular spaces and their role in the glymphatic system and to understand pathologic manifestations of perivascular spaces in various disease processes associated with glymphatic dysfunction, and their possible underlying mechanisms
Keywords: AD = Alzheimer disease; ALPS = analysis along the perivascular spaces; CLIPPERS = chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids; CVS = central vein sign; DTI-ALPS = DTI analysis along the perivascular spaces; DWI-ALPS = DWI analysis along the perivascular spaces; EGFRm-NSCLC = epidermal growth factor receptor‐mutated non-small-cell lung cancer; GAG = glycosaminoglycans; GBCA = gadolinium-based contrast agent; GTPS = giant tumefactive perivascular spaces; LYG = lymphomatoid granulomatosis; MPS = mucopolysaccharidoses; MVNT = multinodular and vacuolating neuronal tumor; NM = neurocutaneous melanosis; PACNS = primary angiitis of the CNS; PD = Parkinson disease; PVS = perivascular spaces; VWI = vessel wall imaging
Document Type: Research Article
Publication date: April 1, 2024
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