@article {Shah:2025:2637-8329:229,
title = "Plexus Puzzles: Unraveling Mysteries with MR Neurography",
journal = "Neurographics",
parent_itemid = "infobike://asnr/ng",
publishercode ="asnr",
year = "2025",
volume = "15",
number = "3",
publication date ="2025-07-01T00:00:00",
pages = "229-238",
itemtype = "ARTICLE",
issn = "2637-8329",
eissn = "2637-8329",
url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2025/00000015/00000003/art00008",
doi = "doi:10.3174/ng.2400067",
keyword = "FS = fat-suppression, AI = artificial intelligence, MADSAM = multifocal acquired demyelinating sensory and motor neuropathy, MMN = multifocal motor neuropathy, SHINKEI = nerve-sheath signal increased with INKed rest-tissue rarE Imaging, EMG = electromyography, MRN = MR neurography, US = ultrasound, FOV = field of view, MENSA = multiecho in steady state acquisition",
author = "Shah, N. and Shah, D. and Doshi, A. and Schecht, M.",
abstract = "MR neurography (MRN) represents an array of techniques to optimize the evaluation for peripheral nerve pathology. The superior resolution of MRN has revolutionized the detection of plexopathy.Advances in neuroimaging have enabled parallel imaging to accelerate the total imaged volume.1
Larger image volumes with an associated increase in spatial resolution allow characterization of nerves of <1 cm. Our institution uses 2 primary MRN plexus protocols, which consist of both 2D and 3D techniques, most importantly focusing on high-resolution thin-slice 3D sequences as well
as nerve-selective sequences.MRN works as an adjunct to nerve ultrasound (US), because it demonstrates improved soft-tissue resolution. MRN also visualize secondary signs of nerve injury/pathology, such as edema or volume loss in the surrounding musculature to indicate acute or chronic
muscle denervation.MRN can be susceptible to a range of artifacts or other pitfalls that can make interpretation challenging. Some of these include the magic angle effect, inhomogeneous fat suppression, susceptibility/chemical shift artifacts, and hyperintense signal in adjacent vasculature.Overall,
MRN is a powerful, noninvasive imaging tool that improves resolution of the plexus anatomy. This allows more pinpoint/directed treatment strategies.Learning Objective: To understand the techniques involved with MRN; explain the anatomy of the brachial, lumbar, and sacral plexus; and describe
pathology that can be detected with MRN.",
}