@article {Siala:2025:2637-8329:164,
title = "Recurrent Stroke-Like Episodes in X-Linked Charcot-Marie-Tooth Type 1 Disease: Characteristic Brain MRI Findings",
journal = "Neurographics",
parent_itemid = "infobike://asnr/ng",
publishercode ="asnr",
year = "2025",
volume = "15",
number = "3",
publication date ="2025-07-01T00:00:00",
pages = "164-168",
itemtype = "ARTICLE",
issn = "2637-8329",
eissn = "2637-8329",
url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2025/00000015/00000003/art00002",
doi = "doi:10.3174/ng.2400044",
keyword = "ADEM = acute disseminated encephalomyelitis, MELAS = mitochondrial encephalopathy with lactic acidosis and stroke-like episodes, ALD = Adrenoleukodystrophy, CMT = Charcot-Marie-Tooth, Cx32 = connexin 32, CMTX = X-linked type of Charcot-Marie-Tooth, CMTX1 = X-linked type of Charcot-Marie-Tooth type 1, CLOCCs = cytotoxic lesions of the corpus callosum, CLOCC = cytotoxic lesion of the corpus callosum",
author = "Siala, S. and Hung, S.-C.",
abstract = "Charcot-Marie-Tooth disease (CMT) comprises a diverse group of hereditary neurologic disorders, predominantly autosomal dominant but also X-linked forms. While CMT primarily affects the peripheral nervous system, the X-linked CMT type 1 (CMTX1) can also cause transient CNS symptoms
and reversible white matter lesions. This case of a young man with transient and recurrent stroke-like neurologic deficits and bilateral white matter signal abnormalities on brain MRI underscores the importance of considering CMTX1 in similar presentations and highlights its typical CNS involvement.",
}