@article {Svec:2023:2637-8329:272, title = "Typical and Atypical Imaging Features of West Nile Neuroinvasive Disease: A Timely Review", journal = "Neurographics", parent_itemid = "infobike://asnr/ng", publishercode ="asnr", year = "2023", volume = "13", number = "4", publication date ="2023-10-01T00:00:00", pages = "272-279", itemtype = "ARTICLE", issn = "2637-8329", eissn = "2637-8329", url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2023/00000013/00000004/art00004", doi = "doi:10.3174/ng.2200022", keyword = "AFP = acute flaccid paralysis, WNV = West Nile virus, WNND = West Nile neuroinvasive disease, AFM = acute flaccid myelitis", author = "Svec, A. and Shroads, M.R. and Ritchie, D.J. and Hughes, J.N.", abstract = "West Nile virus is the most common arbovirus in the continental United States and one of the most common throughout the world. Less than 1% of West Nile virus infections result in West Nile neuroinvasive disease. Patients characteristically present with meningitis, encephalitis, or acute flaccid myelitis, but they may have a variable clinical course and corresponding imaging manifestations. The radiologist plays an important role in making this often-elusive diagnosis. Understanding the imaging features of typical and atypical West Nile neuroinvasive disease is crucial to making a timely diagnosis, which can help prevent additional, potentially harmful testing or treatment. In this review, the authors summarize their experience with West Nile neuroinvasive disease imaging during a surge of cases at their institution.Learning Objective: To identify the typical and atypical imaging appearances of West Nile virus neuroinvasive disease, to understand the differential diagnosis when a patient presents with typical imaging features of West Nile virus infection, and to recognize the environmental factors responsible for seasonal variations in West Nile virus infections", }