@article {Sachs:2023:2637-8329:110, title = "Is It Intracranial Hemorrhage? A Case-Based Approach to Confident Determination Using Dual-Energy CT", journal = "Neurographics", parent_itemid = "infobike://asnr/ng", publishercode ="asnr", year = "2023", volume = "13", number = "2", publication date ="2023-04-01T00:00:00", pages = "110-122", itemtype = "ARTICLE", issn = "2637-8329", eissn = "2637-8329", url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2023/00000013/00000002/art00005", doi = "doi:10.3174/ng.2200008", keyword = "VMI = virtual monoenergetic image, SECT = single-energy CT, VNC = virtual noncontrast, DECT = dual-energy CT, VNCa = virtual noncalcium, ED = emergency department", author = "Sachs, J.R. and Bunch, P.M. and Sweeney, A.P. and Hiatt, K.D. and Benayoun, M.D. and West, T.G.", abstract = "Differentiating acute hemorrhage from hyperattenuating mimics remains a common problem in neuroradiology practice. High atomic number materials such as iodine, calcium, and silicone oil can be similar in attenuation to acute blood products, depending on their concentration. Dual-energy CT allows differentiation of hemorrhage from these high atomic number materials because of the differential absorption of x-ray photons at different incident energies. The primary purpose of this case review is to illustrate how to confidently and efficiently use 190-keV virtual monoenergetic images and material decomposition maps in routine neuroradiology practice when the differential diagnosis includes hemorrhage versus a high atomic number hyperattenuating mimic. We review the underlying physics of dual-energy CT, the primary output of dual-energy postprocessing, as well as pitfalls.Learning Objective: To learn how to use dual-energy CT to confidently and efficiently differentiate acute hemorrhage and hyperattenuating mimics (eg, calcification or iodinated contrast)", }