@article {Nickerson:2022:2637-8329:71, title = "High-Grade Glial Tumors Associated with ETV6-NTRK3 Gene Fusion: Imaging Appearance with Pathologic Correlate", journal = "Neurographics", parent_itemid = "infobike://asnr/ng", publishercode ="asnr", year = "2022", volume = "12", number = "2", publication date ="2022-04-01T00:00:00", pages = "71-78", itemtype = "ARTICLE", issn = "2637-8329", eissn = "2637-8329", url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2022/00000012/00000002/art00002", doi = "doi:10.3174/ng.2000068", keyword = "TRK = tropomyosin receptor kinase", author = "Nickerson, J.P. and Wood, M. and Mossa-Basha, M. and Filippi, C.G. and Zarnow, D. and Ji, J. and Biegel, J.A. and Akkari, Y. and Ishak, G. and Barajas, R.", abstract = "Genetic analysis of high-grade glial tumors in children has revealed the presence of the ETV6-NTRK3 gene fusion in a small number of highly aggressiveappearing neoplasms. Identification of this gene fusion is important in that these patients may benefit from new, targeted therapies. Clinical presentation, imaging, and pathologic confirmation were obtained from 5 patients with confirmed ETV6-NTRK3 gene fusion. This case series may raise awareness of this entity and prompt genetic evaluation.", }