Sinonasal Teratocarcinosarcoma with Intracranial Extension: A Case Report with Discussion of Imaging and Histopathologic Correlates

Sinonasal teratocarcinosarcoma is a rare, malignant neoplasm of the head and neck, and a locally aggressive tumor with a poor prognosis. Few case reports have been published. We present a case of recurrent sinonasal teratocarcinosarcoma in a 39-year-old man with extension into the intracranial compartment. Here we discuss the histopathologic characteristics and nonspecific imaging features, with key differential considerations, including squamous cell carcinoma, adenocarcinoma, sinonasal undifferentiated carcinoma, esthesioneuroblastoma, and lymphoma. Treatment is ultimately composed of surgical resection and chemoradiation therapy.