@article {Naidich:2018:2637-8329:298,
title = "The Olfactory System: Part III: Central Processing of Olfaction and Central Olfactory Dysfunction",
journal = "Neurographics",
parent_itemid = "infobike://asnr/ng",
publishercode ="asnr",
year = "2018",
volume = "8",
number = "4",
publication date ="2018-08-01T00:00:00",
pages = "298-316",
itemtype = "ARTICLE",
issn = "2637-8329",
eissn = "2637-8329",
url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2018/00000008/00000004/art00008",
doi = "doi:10.3174/ng.1800028",
keyword = "PPC = posterior piriform cortex, MDT = mediodorsal thalamic nucleus, PD = Parkinson disease, OT = olfactory tubercle, OFC = orbitofrontal cortex, Aβ = amyloid-β, CoAm = cortical amygdaloid nucleus, LEC = lateral entorhinal cortex, REM = rapid eye movement, OB = olfactory bulb, PC = piriform cortex, AON = anterior olfactory nucleus, UPSIT = University of Pennsylvania Smell Identification Test, GABA = gamma-amino butyric acid, AD = Alzheimer disease, EC = entorhinal cortex, TAAR = trace amine-associated receptor, QR Code = quick response code, APC = anterior piriform cortex, In = agranular/dysgranular insula, DS = down syndrome",
author = "Naidich, T.P. and Som, P.M.",
abstract = "Parts I and II of this review discussed the detection of odor molecules within the primary olfactory mucosa of the nose, the transfer of the odorant data to the olfactory bulb, and the initial processing of the olfactory data within the bulb. Part III now extends that discussion inward
and addresses the central processing of olfactory data by the primary olfactory cortex and further processing by secondary olfactory cortices and related portions of the brain. It then addresses the intriguing links among olfactory dysfunction, sleep disturbance, dementias, and psychoses.Learning
Objective: This review is intended to help the reader: 1) to become familiar with the olfactory structures of the brain, 2) to understand how the brain transforms the physicochemical signature of an odorant molecule and/or mixture into the unified perception of an odor object
that is imbued with salience, valence, and memory associations, and 3) to become aware of the intriguing links among olfactory dysfunction, sleep disturbance, dementias, and psychoses.",
}