@article {Kalnins:2012:2637-8329:106, title = "Neuroradiologic Imaging Findings in Histiocytosis Syndromes in Children and Young Adults", journal = "Neurographics", parent_itemid = "infobike://asnr/ng", publishercode ="asnr", year = "2012", volume = "2", number = "3", publication date ="2012-09-01T00:00:00", pages = "106-118", itemtype = "ARTICLE", issn = "2637-8329", eissn = "2637-8329", url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2012/00000002/00000003/art00003", doi = "doi:10.3174/ng.3120035", keyword = "FHL = familial hemophagocytic lymphohistiocytosis, FDG = fluorodeoxyglucose, HLH = hemophagocytic lymphohistiocytosis, ADEM = acute disseminated encephalomyelitis, RES = reticuloendothelial system, TB = tuberculosis, SHML = sinus histiocytosis with massive lymphadenopathy, LCH = Langerhans cell histiocytosis, DI = diabetes insipidus, MAHS = malignancy-associated hemophagocytic syndrome, CN = cranial nerve, sHLH = secondary hemophagocytic lymphohistiocytosis, VAHS = virus-associated hemophagocytic syndrome", author = "Kalnins, Aleksandrs U. and Mansour, Asem and Castillo, Mauricio", abstract = "There are 2 major subtypes of histiocytosis syndrome in children and adults, classified according to their cellular basis: disorders of varied biologic behavior (dendritic cellrelated or macrophage-related) and malignant disorders (monocyte-related, dendritic cellrelated histiocytic sarcoma, or macrophage-related histiocytic sarcoma). While some neuroradiologic manifestations of histiocytosis syndromes are more closely linked to the underlying pathophysiology, others are less well-defined and remain within a broader differential diagnostic consideration. The underlying epidemiology, pathophysiology, and known radiologic manifestations are reviewed to aid the neuroradiologist in considering the diagnosis of histiocytosis in the appropriate clinical setting.", }