@article {Guleria:2012:2637-8329:64, title = "Neuroimaging Findings in Toxic Brain Injuries", journal = "Neurographics", parent_itemid = "infobike://asnr/ng", publishercode ="asnr", year = "2012", volume = "2", number = "2", publication date ="2012-06-01T00:00:00", pages = "64-76", itemtype = "ARTICLE", issn = "2637-8329", eissn = "2637-8329", url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2012/00000002/00000002/art00004", doi = "doi:10.3174/ng.2120027", keyword = "MELAS = mitochondrial encephalopathy, lactic acidosis, and strokelike episodes, ODMS = osmotic demyelination syndrome, CNS = central nervous system, FLAIR = fluid-attenuated inversion recovery, PRES = posterior reversible encephalopathy syndrome, MBD = Marchiafava-Bignami disease, MTX = methotrexate, DWI = diffusion-weighted imaging, WE = Wernicke encephalopathy, TIWI = T1-weighted imaging, GRE = gradient-recalled echo, ADC = apparent diffusion coefficient, DKA = diabetic ketoacidosis", author = "Guleria, Saurabh and Kelly, Teresa G. and Baruah, Dhiraj and Maheshwari, Mohit and Segall, Hervey D.", abstract = "The neurotoxic effects of various drugs and metabolites are often overlooked in the larger picture of complex medical problems. However, with the advent of novel MR imaging techniques, these neurologic effects are being increasingly recognized. These agents include exogenous and endogenous metabolites, and their manifestations may be subtle to recognize. The reversibility of their neurotoxic effects depends on prompt radiologic recognition of the neuroimaging findings to alert the ordering physicians and to initiate appropriate therapy. In this article, the neurotoxic potential of various metabolites is presented and their MR imaging findings are summarized.", }