@article {Ratcliffe:2011:2637-8329:17,
title = "Demyelinating Disorders of the Adult Central Nervous System: A Pictorial Review of MR Imaging Findings",
journal = "Neurographics",
parent_itemid = "infobike://asnr/ng",
publishercode ="asnr",
year = "2011",
volume = "1",
number = "1",
publication date ="2011-06-01T00:00:00",
pages = "17-30",
itemtype = "ARTICLE",
issn = "2637-8329",
eissn = "2637-8329",
url = "https://asnr.publisher.ingentaconnect.com/content/asnr/ng/2011/00000001/00000001/art00003",
doi = "doi:10.3174/ng.1110003",
keyword = "DWI = diffusion-weighted imaging, PML = progressive multifocal leukoencephalopathy, CNS = central nervous system, MS = multiple sclerosis, HIV = human immunodeficiency virus, ADEM = acute disseminated encephalomyelitis, NMO = neuromyelitis optica, FLAIR = fluid-attenuated inversion recovery, IgG = immunoglobulin G, HAART = highly active antiretroviral therapy, IRIS = immune reconstitution inflammatory syndrome, CADASIL = cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, AIDS = acquired immune deficiency syndrome, PRES = posterior reversible encephalopathy syndrome",
author = "Ratcliffe, Michael R. and Al-Islam, Shofiq and Stockley, Hannah M. and Saravanan, Munusamy and Turnbull, Ian W.",
abstract = "CNS demyelinating disorders encompass a wide spectrum of syndromes affecting the integrity of myelin in the brain. These disorders can be classified into primary and secondary processes with secondary causes being further subclassified into infectious, alcohol-related, iatrogenic/toxic,
and vascular, depending on the etiology. Unfortunately, the imaging appearances of the resulting white matter lesions are often nonspecific in nature. An understanding of the clinical features and parenchymal patterns of involvement of demyelinating diseases is essential to permit the radiologist
to generate a narrow differential diagnosis, which the clinician can refine further with knowledge of the patient's history and laboratory testing. This pictorial review presents the imaging features of demyelinating disorders. Imaging features allowing their optimal differentiation will be
discussed.",
}